Higher PEEP improves outcomes in ARDS patients with clinically objective positive oxygenation response to PEEP: a systematic review and meta-analysis

Abstract Background Mortality in patients with acute respiratory distress syndrome (ARDS) remains high.These patients require mechanical ventilation strategies that include high positive end-expiratory pressure (PEEP).It remains controversial whether high PEEP can improve outcomes for ARDS patients, especially patients who show improvement in oxyge

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Terahertz-assisted even harmonics generation in silicon

Summary: When a Queen Upholstered Headboard biased electric/light field is applied to centrosymmetric crystals like silicon, the broken symmetry creates even-order harmonics radiation which can reveal key insights into the material.Recently, the second harmonic has been generated by THz-induced symmetry breaking, but the observation of higher-order

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Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy research.Increasingly used to advance this field, the genetically audiogenic seizure hamster from Salamanca (GASH/Sal) exhibits generalized seizures triggered by high-i

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